11th International Consensus Conference on Outcome Measures in Rheumatology
Pinehurst, North Carolina, USA
May 12-17, 2012

Introduction
Lee S. Simon, Vibeke Strand, Clifton O. Bingham III, and Jasvinder A. Singh.........145
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Methods

Including Health Equity Considerations in Development of Instruments for Rheumatology Research: An Introduction to a Novel OMERACT Paradigm
Jennifer O’Neill, Tamara Rader, Francis Guillemin , Annelies Boonen, Robin Christensen, Anne Lyddiatt, Jordi Pardo Pardo, Vivian Welch, Jasvinder A. Singh, and Peter Tugwell.........150
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Item Response Theory, Computerized Adaptive Testing, and PROMIS: Assessment of Physical Function
James F. Fries, James Witter, Matthias Rose, D. Khanna, E. Morgan-DeWitt.........153
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A Systematic Literature Review on the Application of Rasch Analysis in Musculoskeletal Disease - A Special Interest Group Report of OMERACT 11
Ying-Ying Leung, May-Ee Png, Philip Conaghan, and Alan Tennant .........159
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Worker Productivity Outcome Measures: OMERACT Filter Evidence and Agenda for Future Research
Kenneth Tang, Annelies Boonen, Suzanne M.M. Verstappen , Reuben Escorpizo, Jolanda J. Luime, Diane Lacaille, Bruno Fautrel, Ailsa Bosworth, Mary Cifaldi, Monique A.M. Gignac, Cathy Hofstetter, Amye Leong, Pam Montie, Ingemar F. Petersson, Oana Purcaru, Claire Bombardier, Peter S. Tugwell, and Dorcas E. Beaton.........165
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What Has Been the Effect on Trial Outcome Assessments of a Decade of Patient Participation in OMERACT?
Maarten P.T. de Wit, Tineke A. Abma, Marije S. Koelewijn-van Loon , S. Collins, J. Kirwan.........177
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Imaging and Other Biomarkers

Selecting MRI Outcome Measures for JIA Clinical Trials: First Report of the MRI in JIA Special Interest Group
Robert Hemke, Andrea S. Doria, Nikolay Tzaribachev, Mario Maas, Désirée M.F.M van der Heijde, and Marion A.J. van Rossum.........354
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Methodologies for Semiquantitative Evaluation of Hip OA by MRI: Approaches Based on the Whole Organ and Focused on Active Lesions
Jacob L. Jaremko, Robert G.W. Lambert, Veronika Zubler , Ulrich Weber, Damien Loeuille, Frank W. Roemer, Jolanda Cibere, Marcus Pianta, David Gracey, Philip Conaghan, Mikkel Ostergaard, and Walter P. Maksymowych.........359
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Preliminary Validation of 2 MRI Scoring Systems for OA of the Hip According to the OMERACT Filter
Walter P. Maksymowych, Jolanda Cibere, Damien Loeuille, Ulrich Weber, Veronika Zubler, Frank W. Roemer, Jacob L. Jaremko, Eric C. Sayre, and Robert G.W. Lambert.........370
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Responsiveness in RA. A Report from the OMERACT 11 Ultrasound Workshop
Annamaria Iagnocco, Esperanza Naredo, Richard Wakefield, George A.W. Bruyn, Paz Collado, Sandrine Jousse-Joulin, Stephanie Finzel, Sarah Ohrndorf, Andrea Delle Sedie, Marina Backhaus, Hilde Berner-Hammer, Frederique Gandjbakhch, Gurjit Kaeley, Damien Loeuille, Ingrid Moller, Lene Terslev, Philippe Aegerter, Sibel Aydin, Peter V. Balint, Emilio Filippucci, Peter Mandl, Carlos Pineda, Johannes Roth, Silvia Magni-Manzoni, Niolay Tzaribachev, Wolfgang A. Schmidt, Philip G. Conaghan, and Maria-Antonietta D’Agostino.........379
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Update on the OMERACT MRI Task Force: Research and Future Directions
Philip G. Conaghan, Fiona M. McQueen, Paul Bird, Charles Peterfy, Espen Haavardsholm, Frédérique Gandjbakhch, Iris Eshed, Ida K. Haugen, Siri Lillegraven, Uffe Møller Døhn, Bo Ejbjerg, Violaine Foltz, Laura Coates, Pernille Bøyesen, Kay-Geert Hermann, Jane Freeston, Marissa Lassere, Philip O’Connor, Paul Emery, Harry Genant, and Mikkel Østergaard.........383
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Iterative Development and Reliability of the OMERACT Hand OA MRI Scoring System
Ida K. Haugen, Mikkel Østergaard, Iris Eshed, Fiona M. McQueen, Paul Bird, Frederique Gandjbakhch, Violaine Foltz, Harry Genant, Charles Peterfy, Siri Lillegraven, Espen A. Haavardsholm, Pernille Bøyesen, and Philip G. Conaghan.........386
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The OMERACT-RAMRIS RA MRI Joint Space Narrowing Score: Intrareader and Interreader Reliability and Agreement with CT and Conventional Radiography
Uffe Møller Døhn, Philip G. Conaghan, Iris Eshed, Annelies Boonen, Pernille Boyesen, Charles G. Peterfy, Siri Lillegraven, Bo Ejbjerg, Frederique Gandjbakhch, Paul Bird, Violaine Foltz, Harry K. Genant, Espen Haavardsholm, Fiona M. McQueen, and Mikkel Østergaard.........392
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Determining a MRI Inflammatory Activity Acceptable State Without Subsequent Radiographic Progression in RA: Results from a Followup MRI Study of 254 Patients in Clinical Remission or Low Disease Activity
Frédérique Gandjbakhch, Espen A. Haavardsholm, Philip G. Conaghan, Bo Ejbjerg, Violaine Foltz, Andrew K. Brown, Uffe Møller Døhn, Marissa Lassere, Jane E. Freeston, Inge Christoffer Olsen, Pernille Bøyesen, Paul Bird, Bruno Fautrel, Merete Lund Hetland, Paul Emery, Pierre Bourgeois, Kim Hørslev-Petersen, Tore K. Kvien, Fiona M. McQueen, and Mikkel Østergaard.........398
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Disease-specific Outcomes I

Outcome Measures in Acute Gout: A Systematic Literature Review
Nicola Dalbeth, Cathy S. Zhong, Rebecca Grainger, Dinesh Khanna, Puja P. Khanna, Jasvinder A. Singh, Fiona M. McQueen, and William J. Taylor .........558
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OMERACT Endorsement of Measures of Outcome for Studies of Acute Gout
Jasvinder A. Singh, William J. Taylor, Nicola Dalbeth, Lee S. Simon, John Sundy, Rebecca Grainger, Rieke Alten, Lyn March, Vibeke Strand, George Wells, Dinesh Khanna, Fiona McQueen, Naomi Schlesinger, Annelies Boonen, Maarten Boers, Kenneth G. Saag, H. Ralph Schumacher, and N. Lawrence Edwards .........569
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Application of the OMERACT Filter to Measures of Core Outcome Domains in Recent Clinical Studies of Acute Gout
William J. Taylor, David Redden, Nicola Dalbeth, H. Ralph Schumacher, N. Lawrence Edwards, Lee S. Simon, Markus R. John, Margaret N. Essex, Douglas J. Watson, Robert Evans, Keith Rome, and Jasvinder A. Singh .........574
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Patient-reported Outcomes and Adult Patients' Disease Experience in the Idiopathic Inflammatory Myopathies. Report from the OMERACT 11 Myositis Special Interest Group
Helene Alexanderson, Maria Del Grande, Clifton O. Bingham III, Ana-Maria Orbai, Catherine Sarver, Katherine Clegg-Smith, Ingrid E. Lundberg, Yeong Wook Song, and Lisa Christopher-Stine .........581
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Current Status of Outcome Measure Development in Vasculitis
Peter A. Merkel, Sibel Z. Aydin, Maarten Boers, Raashid Luqmani, Eric L. Matteson, Nataliya Milman, Joanna Robson, Philip Seo, and Gunnar Tomasson.........593
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Outcome Measures Used in Clinical Trials for Behçet Syndrome: A Systematic Review
Gulen Hatemi, Peter A. Merkel, Vedat Hamuryudan, Maarten Boers, Haner Direskeneli, Sibel Z. Aydin, and Hasan Yazici .........599
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Disease-specific Outcomes II

Development of a Disease Activity and Responder Index for PsA — Report of the PsA Module at OMERACT 11
Laura C. Coates, Oliver FitzGerald, Philip J. Mease, Dafna D. Gladman, Vibeke Strand, Niti Goel, Ina Campbell, Gerald Krueger, Neil J. McHugh, and Philip S. Helliwell .........782
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Reconciling Healthcare Professional and Patient Perspectives in the Development of Disease Activity and Response Criteria in Connective Tissue Disease–related Interstitial Lung Diseases
Lesley Ann Saketkoo, Shikha Mittoo, Sid Frankel, Daphne LeSage, Catherine Sarver, Kristine Phillips, Vibeke Strand, Eric L. Matteson, the OMERACT Connective Tissue Disease–Interstitial Lung Diseases Working Group.........792
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Establishing a Core Domain Set to Measure RA Flares: Report of the OMERACT 11 RA Flare Workshop
Vivian P. Bykerk, Elisabeth Lie, Susan J. Bartlett, Rieke Alten, Annelies Boonen, Robin Christensen, Daniel E. Furst, Sarah Hewlett, Amye L. Leong, Anne Lyddiatt, Lyn March, James E. May, Pam Montie, Ana-Maria Orbai, Christoph Pohl, Marieke Scholte Voshaar, Thasia Woodworth, Clifton O. Bingham III, and Ernest H. Choy.........799
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Report from the OMERACT Hand OA Special Interest Group: Advances and Future Research Priorities
Margreet Kloppenburg, Pernille Bøyesen, Wilma Smeets, Ida Haugen, Rani Liu, Willemien Visser, and Désirée M. van der Heijde.........810
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Polymyalgia Rheumatica (PMR) Special Interest Group at OMERACT 11: Outcomes of Importance for Patients with PMR
Sarah L. Mackie, Seher Arat, Jose da Silva, Catia Duarte, Sue Halliday, Rod Hughes, Marianne Morris, Colin T. Pease, Jeffrey W. Sherman, Lee S. Simon, Maggie Walsh, René Westhovens, Samy Zakout, and John R. Kirwan.........819
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Omeract Filter 2.0

Updating the OMERACT Filter at OMERACT 11
John R. Kirwan, Maarten Boers, and Peter Tugwell.........975
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Toward a Generalized Framework of Core Measurement Areas in Clinical Trials: A Position Paper for OMERACT 11
Maarten Boers, Leanne Idzerda, John R. Kirwan, Dorcas Beaton, Reuben Escorpizo, Annelies Boonen, Susan Magasi, Ian Sinha, Gerold Stucki, and Peter Tugwell .........978
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Can We Decide Which Outcomes Should Be Measured in Every Clinical Trial? A Scoping Review of the Existing Conceptual Frameworks and Processes to Develop Core Outcome Sets
Leanne Idzerda, Tamara Rader, Peter Tugwell, and Maarten Boers .........986
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Updating the OMERACT Filter: Core Areas as a Basis for Defining Core Outcome Sets
John R. Kirwan, Maarten Boers, Sarah Hewlett, Dorcas Beaton, Clifton O. Bingham III, Ernest Choy, Philip G. Conaghan, Maria-Antonietta D’Agostino, Maxime Dougados, Daniel E. Furst, Francis Guillemin, Laure Gossec, Désirée M. van der Heijde, Margreet Kloppenburg, Tore K. Kvien, Robert B.M. Landewé, Sarah L. Mackie, Eric L. Matteson, Philip J. Mease, Peter A. Merkel, Mikkel Ostergaard, Lesley Ann Saketkoo, Lee Simon, Jasvinder A. Singh, Vibeke Strand, and Peter Tugwell.........994
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Updating the OMERACT Filter: Implications of Filter 2.0 to Select Outcome Instruments Through Assessment of "Truth": Content, Face, and Construct Validity
Peter Tugwell, Maarten Boers, Maria-Antonietta D’Agostino, Dorcas Beaton, Annelies Boonen, Clifton O. Bingham III, Ernest Choy, Philip G. Conaghan, Maxime Dougados, Catia Duarte, Daniel E. Furst, Francis Guillemin, Laure Gossec, Turid Heiberg, Désirée M. van der Heijde, Sarah Hewlett, John R. Kirwan, Tore K. Kvien, Robert B. Landewé, Philip J. Mease, Mikkel Østergaard, Lee Simon, Jasvinder A. Singh, Vibeke Strand, and George Wells .........1000
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Updating the OMERACT Filter: Discrimination and Feasibility
George Wells, Dorcas E. Beaton, Peter Tugwell, Maarten Boers, John R. Kirwan, Clifton O. Bingham III, Annelies Boonen, Peter Brooks, Philip G. Conaghan, Maria-Antonietta D’Agostino, Maxime Dougados, Daniel E. Furst, Laure Gossec, Francis Guillemin, Philip Helliwell, Sarah Hewlett, Tore K. Kvien, Robert B. Landewé, Lyn March, Philip J. Mease, Mikkel Ostergaard, Lee Simon, Jasvinder A. Singh, Vibeke Strand, and Désirée M. van der Heijde.........1005
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Updating the OMERACT Filter: Implications for Patient-reported Outcomes
John R. Kirwan, Susan J. Bartlett, Dorcas E. Beaton, Maarten Boers, Ailsa Bosworth, Peter M. Brooks, Ernest Choy, Maarten de Wit, Francis Guillemin, Sarah Hewlett, Tore K. Kvien, Robert B. Landewé, Amye L. Leong, Anne Lyddiatt, Lyn March, James May, Pamela Lesley Montie, Enkeleida Nikaï, Pam Richards, Marieke M.J.H. Voshaar, Wilma Smeets, Vibeke Strand, Peter Tugwell, and Laure Gossec.........1011
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Updating the OMERACT Filter: Implications for Imaging and Soluble Biomarkers
Maria-Antonietta D’Agostino, Maarten Boers, John Kirwan, Désirée van der Heijde, Mikkel Østergaard, Georg Schett, Robert B. Landewé, Walter P. Maksymowych, Esperanza Naredo, Maxime Dougados, Annamaria Iagnocco, Clifton O. Bingham III, Peter M. Brooks, Dorcas E. Beaton, Frederique Gandjbakhch, Laure Gossec, Francis Guillemin, Sarah E. Hewlett, Margreet Kloppenburg, Lyn March, Philip J. Mease, Ingrid Moller, Lee S. Simon, Jasvinder A. Singh, Vibeke Strand, Richard J. Wakefield, George A. Wells, Peter Tugwell, and Philip G. Conaghan.........1016
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How to Choose Core Outcome Measurement Sets for Clinical Trials: OMERACT 11 Approves Filter 2.0
Maarten Boers, John R. Kirwan, Laure Gossec, Philip G. Conaghan, Maria-Antonietta D’Agostino, Clifton O. Bingham III, Peter M. Brooks, Robert Landewé, Lyn March, Lee Simon, Jasvinder A. Singh, Vibeke Strand, George A. Wells, and Peter Tugwell .........1025
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